Samurai Deeper Kyou begins four years after that battle, when a gun-wielding bounty hunter by the name of Yuya Shiina hunts down Kyoushirou-now a perverted, traveling medicine-man who has built up a large debt. Their legendary clash was cut short when a meteor from the heavens fell down upon that battlefield, leaving both to vanish in its wake. The other was the thousand-man slayer, with eyes and hair the color of blood, 'Demon Eyes' Kyou. One was Kyoushirou Mibu, a skilled and noble warrior in possession of the unique powers of the Mibu Clan.
In the year 1600, at the fog-covered battlefield of Sekigahara, a fierce battle was waged by two exemplary swordsmen.